A woman who suffered from a rare condition which made her grow into a 6ft 11ins giant has died suddenly at the age of 34.
Tanya Angus, from Las Vegas, spent the last 12 years trying to find a cure for her acromegaly, which meant she couldn't stop growing.
Until the age of 21, Tanya was just 5ft 8ins tall and weighed 130lbs. She rode horses, went dancing and had a boyfriend.
Tanya, who became wheelchair-bound, had the most extreme form of acromegaly ever seen, growing to nearly 7ft tall, and more than 400lbs.
Ms Angus, who had been working as a supervisor at a Walmart in Michigan, was fired from her post when her condition worsened, and was dumped by her boyfriend when his parents questioned whether she was a man.
In August last year, it seemed like Tanya and her family had finally seen a breakthrough, when a blood test revealed that her growth hormone levels had fallen at last.
Tanya's mother Karen Strutynski said at the time: 'For the first time ever, Tanya's blood level for her disease is in the normal range.
'It gives us renewed hope and will give other people renewed hope.'
It is thought the extreme pressure on her body, caused by 12 years of coping with her huge size, caused her heart to fail.
A notice on Tanya's website, which has inspired and helped acromegaly sufferers around the world, reads simply: 'It is with deep sorrow that we announce the passing on of our beloved Tanya Angus at 12.25am on January 14, 2013, due to her heart and TIA. RIP dear one'
Transient Ischemic Attack (TIA) is a type of mini-stroke, caused when the blood flow to the brain stops for a period of time.
Tanya had suffered a number of TIAs in recent years.
'I read emails that people send in saying: ''You're my inspiration,'' or, ''You are so strong.''
'If I am helping other people, I feel I can do anything.'
Tanya, whose condition caused her to spend many hours sleeping, found her outlet through her website, which helped her gain friends around the world.
Last year, she was able to meet some of them for the first time at an Acromegaly Conference in Las Vegas, where fellow sufferers told Tanya how hearing her story had caused them to seek early treatment, and possibly saved their lives.
During the last 12 years, Tanya underwent three operations to attempt to remove her tumour, but several different surgeons were unable to reach part of the growth, as it was wrapped around her inner carotid artery.
Her heart, lungs and the joints of her limbs continued to grow as she gained weight and height, causing huge strain on her body.
The treatment seemed to finally be working, until the sad news in October that her growth hormone levels were rising again.
Tanya, talking in 2009 about the slow onset of her growth said: 'I couldn't understand why, as I wasn't eating more. What was strange was that my feet seemed to grow as well. My face also started to swell and was changing.
'I felt unhappy with my appearance and spent a fortune on make-up. My figure also started to change and become more manly and my voice became deeper.'
The 34-year-old, who loved jewellery and enjoyed regular swimming sessions which helped her body feel weightless, continued to remain hopeful throughout her life.
'Without hope you don't have anything,' she is quoted as saying. 'I hope they can stop me growing one day.'